BDBM348948 N-(5-(4-((1,5-dimethyl-1H- pyrazol-3-yl)methyldimethyl- 1H-pyrazol-3- yl)methoxy)phenyl)- [1,2,4]triazolo[1,5-a]pyridin-2- yl)cyclopropanecarboxamide::US10206907, Compound 62

SMILES Cc1cc(COc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)nn1C

InChI Key InChIKey=WQNDDEXIIMVAAD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 348948   

TargetNon-receptor tyrosine-protein kinase TYK2 [871-1187](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM348948(N-(5-(4-((1,5-dimethyl-1H- pyrazol-3-yl)methyldime...)
Affinity DataIC50: >1.00E+3nMAssay Description:Recombinant human TYK2 catalytic domain (amino acids 871-1187; catalog number 08-147) was purchased from Carna biosciences. 5 ng of TYK2 was incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent